Daniel McQueen utilizes mindfulness-enhanced psychedelic therapy and multimodal, multi-substance programs to provide comprehensive, trauma-informed healing and advanced spiritual exploration. Through his innovative work with psychedelic cannabis blends and extended-state DMTx journeys, McQueen emphasizes safety, client autonomy, and deeply ethical facilitation practices, while keeping a healthy curiosity of psychedelic medicine and what it can achieve.
Key Takeaways
- Psychedelic Cannabis is a Distinct Modality: By intuitively blending full-spectrum sativa, indica, and hybrid strains, Daniel McQueen developed a somatic, trauma-informed practice that induces a waking, dream-like state capable of psychedelic visuals with client autonomy fully intact.
- DMTx Extends the Psychedelic Journey: To overcome the brief 5-to-15-minute window of standard DMT, McQueen pioneered “DMTx,” a multi-hour experience utilizing an infusion pump method that allows journeyers to ground into and explore the space over an extended period.
- The Foundation of Deep Healing is Skill and Ethics: Daniel believes that deep healing relies heavily on the “Set, Setting, and Skill” framework, where established everyday mindfulness practices enhance a client’s ability to surrender to the experience.
- Psychedelic Passage: Your Psychedelic Concierge — The easy, legal way to find trustworthy psilocybin guides, facilitators, and psychedelic-assisted therapy near you in the United States.
Daniel McQueen is a well-established psychedelic facilitator, researcher, and mentor with nearly 30 years of psychedelic experience, 17 of those as a professional guide. Living in Colorado, he saw the slow progression of the legalization of cannabis and other natural medicines like psilocybin and DMT under the “Natural Medicine Health Act”, also known as “Prop 122”.
Daniel has a master’s degree in Transpersonal Counseling Psychology from Naropa University and specializes in treating acute cases of PTSD and generational trauma, and is also interested in using psychedelic medicines for critical problem-solving.
He is the author of Psychedelic Cannabis: Unique Blends and Therapeutic Techniques to Treat Trauma and Transform Consciousness, and started an international movement of practitioners using cannabis as a classic psychedelic in professional settings. He is currently working on his second book, Safe Travels: A Psychedelic Community Survival Guide, exploring safe psychedelic use practices and community sustainability agreements.
Through one of his organizations, DMTx, he is a lead DMT guide, psychedelic specialist, and chaplain. He has directly led over 30 DMT journeys in skillful, individually guided sessions. He guides journeyers using advanced Mindfulness-Based Psychedelic Therapy techniques, a somatic, trauma-informed, arts-integrated, and transpersonal psychedelic therapy practice that he has been teaching to psychedelic guides for the last 14 years.
Daniel is supported by a team of guides, medical providers, and an awesome staff that keeps their ship sailing, including his wife Alison McQueen, MA, LPC, Approved Clinical Supervisor, Board Certified Art Therapist, Licensed Natural Medicine Clinical Facilitator, and Clinical Director of the Center for Medicinal Mindfulness, which they cofounded together.
Daniel is the father of two glorious children, to whom he devotes his work in the world, and he recognizes the unique opportunity he has been given to do the work that he does. In his own words, “it is a privilege beyond belief” that he can openly practice as a psychedelic guide in his hometown.
Journey into a conversation with us as we delve into his work using cannabis as a psychedelic, elongated DMT sessions, and what it’s like being a psychedelic professional in a legal state.
This article is inspired by our insightful podcast episode hosted by Psychedelic Passage co-founder, Jimmy Nguyen, which you can listen to on all streaming platforms.
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What is Psychedelic Cannabis?
Before founding Psychedelic Passage in 2019, our founder, Jimmy Nguyen, used to work in the cannabis industry in Colorado after it became legalized. At this time, Daniel had already co-founded the Center for Medicinal Mindfulness with his wife, Alison, and would frequently run events called “Conscious Cannabis Circle.”
You see, years earlier, Daniel had found a way to produce a psychedelic experience solely from smoking cannabis. In his own words, it was “Spirit” that told him to combine multiple cannabis strains in order to achieve a similar experience to DMT or ayahuasca, yet with the journeyer retaining much more agency.
As he began creating these blends, he gave them to friends interested in seeing what this new discovery was all about. One friend said, “Daniel, if I didn’t trust you and knew you as a friend, I would have sworn you put DMT in that.” It was remarks like this that greatly sparked Daniel’s interest in the psychedelic capabilities of cannabis.
Conscious Cannabis Circles and Daniel’s Impact on Jimmy
In a Conscious Cannabis Circle, Daniel combines anywhere from 3-16 cannabis strains, grinding them until they are sufficiently combined, and then offering the combination to attendees to be smoked or vaped. When prepared in this manner, he refers to it as “psychedelic cannabis.”
The key is to choose a mix of strains that offer a wide, full-spectrum combination of constituents from sativa, hybrid, and indica strains. These strains should be stronger, with a THC content of 22% or more.
First, one would pick a younger or more recently harvested, anxiety-inducing sativa strain like Durban Poison, Ghost Train Haze, or Blue Dream. Daniel says the ideal sativa in this case would be one that would normally be extremely anxiety-inducing and perhaps a bit intimidating.
Then, one would pick an indica strain, like one of the Kush varieties or Northern Lights, that has preferably been sitting around for a while. This is due to the fact that THC degrades over time, turning into CBN (Cannabinol), which has sedative effects that neutralize the anxiety-inducing effects of the sativa strain.
After sativa and indica strains are chosen, one would select a hybrid strain that resonates with them to further enhance the profile of the strain mixture, resulting in the positive benefits of each strain while each strain counteracts the potential negative effects of the others. You would then lie down with your eyes covered and consume the cannabis by smoking it.
An important note on tolerance: For someone who has never smoked or hasn’t smoked in a few months, they may only need one or two puffs, while someone who is a daily smoker could need many more puffs to achieve a psychedelic cannabis experience. Do not underestimate the strength of cannabis, especially to someone without a tolerance to it (isn’t a daily smoker). If you’re unsure, start with one puff.
Music accentuates a psychedelic cannabis experience and is highly recommended. If you’re looking for more information on this topic, Daniel’s book, Psychedelic Cannabis covers this process extensively.
For those with a high tolerance, Daniel welcomes titrating your dosing and taking more hits over time if you aren’t achieving the desired results. Breathing techniques can also come into play to help relax into the psychedelic cannabis experience.
These blends should be created intuitively, and Daniel likes to follow his nose, picking strains whose aromas interest him. If you’re new to cannabis, Daniel recommends going to a dispensary that has their bud in jars so you can smell each strain.
Pick the budtenders’ brains; see what strains are their favorite and what they recommend for various things, they should be well-versed in cannabis and the products they have available.
So what do you get when you follow this protocol? The feeling of being deeply relaxed while your mind is wide awake. While the sativa is turning up the energy and creativity, the indica allows for the brain to fall into a more meditative state.
The closed-eye visuals increase, but if you were to sit up, you would come back to a sober reality, still feeling quite “stoned,” but not under the psychedelic veil that overshadows reality when you take something like psilocybin.
Funnily enough, back in 2016, when they were both working in Colorado, Jimmy’s boss in the cannabis industry reached out to Daniel to organize a work retreat, “Conscious Cannabis Circle,” for his employees.
For this particular event, they were able to use the cannabis that Jimmy’s workplace grew, which gave the experience more depth, as the same people who watched these plants grow from a seed to THC-riddled nugs of greenery, caring for each plant along the way, were about to have profound experiences with the very plants they grew.
Recommended Reading: What is Cannabis-Assisted Psychotherapy & Where to Find it
What’s the Role of the Nervous System in Psychedelic Cannabis?
So how exactly does the whole psychedelic cannabis thing work? Our nervous system might play a greater role than one might think.
Combining multiple strains of cannabis in this way activates both sides of our nervous system. While the activation of our sympathetic nervous system creates a hyper-alertness, activation of the parasympathetic side results in a dream-like state. Daniel compares it to a “lucid, waking dream state with a psychedelic theme to it.”
The idea of being in a waking, dream-like state isn’t exactly new, and you may have experienced this going to bed while being a bit overtired. We call it a hypnagogic state, and ordinarily, being in this state can result in involuntary, imagined visual experiences.
In McQueen’s line of work, cannabis is often seen as a somatic psychedelic and can result in experiences similar to that of somatic experiencing, first developed by Dr. Peter Levine, as a body-based therapy to process and release trauma. You may have heard of his book, Waking the Tiger: Healing Trauma.
According to somatic experiencing, after a traumatic event, the body’s stress system is stuck permanently overreacting, leading to “a persistent somatic and emotional dysregulation of the nervous system and results in the chronically increased stress reaction that is observed in clients with PTSD” (Kuhfuß, M., et al 2021).
By paying attention to internal and bodily sensations rather than the cognitive and emotional sensations associated with their trauma, one can gradually lower their arousal. Unlike exposure therapy, reliving traumatic memories is avoided and unnecessary in somatic experiencing therapy.
This, paired with new corrective interoceptive experiences that are introduced, help clients with PTSD stop their symptoms without directly dealing with the emotional content associated with them.
Psychedelic cannabis can also release trauma without having to directly experience it. Cannabinoids reduce innate tension in the body via shaking or trembling, and it basically comes down to the body resetting from old injuries.
Big experiences generally hold big emotions, and when people relive old memories, it’s like the body is addressing something it’s been holding on to for a while. You may want to resist shaking if it happens to you during a psychedelic experience, but Daniel welcomes leaning into it instead of trying to control it.
In Daniel’s experience facilitating with psychedelic cannabis, allowing for this physical release can help initiate a more DMT-like experience. Somatic psychedelic cannabis experiences are actually a big part of what facilitators at Daniel’s center do, especially with trauma.
“If all you did was shake during the session, you’d have an incredibly successful journey.” — Daniel McQueen
Interestingly, trauma doesn’t always have to be relived to be processed, and shaking can process a lot of trauma unconsciously. This can be tremendously helpful in instances where reliving the trauma would just cause more harm than good, and it’s also a really important part of healing to emphasize: You do not need to relive your trauma to heal from it.
“The body keeps the score” is a common phrase in trauma work because it really seems to be true. Have you ever put on Animal Planet and there just so happens to be a gazelle running for its life, a lioness close on its tail?
Except by some miracle, it escapes, losing the lioness in the brush. The lioness moves on, and then the camera pans to the gazelle, lying down under a tree, shaking viciously.
The theory behind Peter Levine’s work is that the gazelle releases the trauma of its near-death experience by shaking; it doesn’t get PTSD, and it’s able to go out into the wild again without being so scared of lions it can’t move.
Instead of immediately releasing our traumatic residue, humans store it in our bodies, and sometimes we need to shake for it to be released.
The reason why shaking releases trauma is up for debate, but what is painfully apparent is that the body-mind connection is no joke.
Some interpretations say that the tissue in our bodies holds the trauma; others disagree. Whether it’s stored in cellular tissue, the dendritic memory of our nervous systems, or elsewhere, there’s still a clear connection between traumatic emotional content and physical release.
Here we arrive at a theme that has appeared over and over in our discussions: Don’t be too hard on yourself while on your healing journey.
Healing is not meant to be taken so seriously as to be detrimental. If you aren’t getting the results you expected, there’s no reason to place blame. Surrendering to the experience is far more important than controlling the experience.
You should have reverence for your healing practices, but that doesn’t mean being hard on yourself or worrying that you’re doing it wrong. Healing isn’t always about reliving a traumatic event.
Often, healing comes from a variety of other experiences, like shaking, having an ecstatic experience, having a mystical experience, laughing uncontrollably, or meeting some elves in a seemingly alternate universe.
In a modality as unique, personally intimate, and truly otherworldly, there’s no right or wrong healing experience. Enjoyment is healing too.
What’s Daniel McQueen’s Mission?
In our interview with Daniel McQueen, Jimmy had a sudden epiphany: it was Daniel who inspired Jimmy to try DMT for the first time, which eventually led to him trying ayahuasca. You can imagine how this may have changed the course of Jimmy’s healing journey and life trajectory.
DMT is a truly unique psychedelic, lasting only 5-10 minutes, being powerful enough to completely alter someone’s visual experience in a matter of seconds, and coming with the lore that if you’re meant to try it, it will find you.
In sharing his origin story with us, Daniel reveals that he always envisioned being an older-brother figure for others on a similar path, sharing as much as he can in hopes that younger generations will have a foundation to build upon and follow the same passion he has for his work.
The intermingling of Jimmy’s origin story with Daniel’s shows that Daniel is living his truth in real time, actively showing others interested in it the path forward through intentional psychedelic use, ethical facilitation, and a deep desire to help others.
Notes From Our Interview
Doing Psychedelics to “Feel Better”
Many people find psychedelic healing in their search to feel better, while other people may be actively searching for their purpose in life or their calling, and there’s definitely some overlap in both populations.
Sometimes, callings come with suffering and sacrifice, so it’s not always about feeling better, rather, feeling better just ends up being a natural side effect of doing the work in psychedelic healing.
Mindfulness Practices to Enhance Psychedelic Practices
In Daniel’s years of being a facilitator, he has noticed a very specific pattern: those who have established mindfulness practices in their everyday lives are able to have deeper psychedelic experiences. They’re also able to surrender and let go of control much more easily than someone who hasn’t.
If you’re thinking about having a psychedelic experience, our network of experienced guides is a good place to start, but it may be beneficial to pick up a mindfulness practice while you’re preparing for your journey. There are numerous forms of mindfulness and you can even create your own based on various practices that resonate with you.
Recommended Reading: How Psychedelics Can Enhance Mindfulness Practices
Using Psychedelics for Feeling Stuck in Psychotherapy
Using multiple modalities in your overall healing journey can be extremely beneficial. This is exactly why Daniel’s center uses mindfulness-enhanced and multi-day, multi-substance programs.
There’s a high probability that those who have done decades of psychotherapy and feel like they can’t make any more progress would benefit from psychedelic therapy. The backdrop of psychotherapy could also give you a unique perspective.
Recommended Reading: How Psychedelics Can Help You Get Unstuck
What Qualities Has Daniel Seen That Allow for Deeper Healing?
McQueen reiterates the importance of mindfulness techniques in being able to handle big emotional states that may come with psychedelic experiences. He’s a big proponent of the phrase Set. Setting. Skill. which means that it’s possible for people to gain a skill set that increases the possibility of a conducive psychedelic experience.
“The work’s easier if you train for it.” —Daniel McQueen
General openness and curiosity are common themes that help perpetuate healing in individuals; here, we return to the concept of being able to surrender to the experience.
Being brave, the ability to face something you know will be difficult, is the last quality that Daniel has seen in beneficial psychedelic experiences.
What’s the Center for Medicinal Mindfulness?
At the Center for Medicinal Mindfulness in Colorado, Daniel and Alison first started using cannabis, and they never expected psilocybin to become legal as it has. As natural medicine became legal and their practice expanded, much of their work has become multimodal.
They currently offer therapy with cannabis, ketamine, psilocybin, and DMT, and will soon offer mescaline and 5-MeO-DMT under their church. Note that the laws in Colorado require psychedelic substances to be all natural medicines, absolutely no synthetic forms.
You can grow and consume your own psilocybin mushrooms in Colorado. This is the federal standard we need to set for cannabis, because let’s not forget, growing your own cannabis is federally illegal.
The treatment plan for each individual varies, as some substances may work better than others for certain situations. It’s not uncommon for someone to undergo a psychedelic cannabis session, then a psilocybin session, then another psychedelic cannabis session over the course of a week. Or, the same plan but replace ketamine with cannabis.
Daniel has found that offering a lighter psychedelic experience before and after a larger one can take the pressure off of trying to “heal all your trauma in one session,” which really isn’t ideal, expected, or necessary. He also finds that not relying too much on a single substance is helpful.
The Future for the Center of Medicinal Mindfulness
In the past decade, Daniel’s “Conscious Cannabis Circles” have slowed down, but, in an effort to curb the price of psychedelic healing, he’s bringing them back. Small group offerings are one way that practitioners have been able to lower the price of psychedelic healing.
Pioneering DMTx
McQueen’s center offers N,N-DMT (DMT) extracted from the root bark of the plant Mimosa Hostilis through the personal use model in Colorado, which allows for sharing these medicines with harm reduction and bona fide support services.
The main complaint with DMT is that the journey ends before it can even begin, with a typical experience lasting just 5–15 minutes.
“When we smoke DMT, it’s so shocking, right? It comes on so fast. It’s like a rocket ship propels you through a wormhole and you’re in another reality within a matter of like fifteen seconds. And then as soon as you start to regulate and orient to this inner space, you come back down.” — Daniel McQueen
Using research by Andrew Gallimore on Rick Strassman’s data on targeted infusions of DMT, they formulated a method that enables multi-hour DMT experiences, dubbed DMTx.
Andrew Gallimore, a historical scholar of DMT and a neurobiologist, has been instrumental in Daniel’s development of DMTx. You may also have heard of Rick Strassman, whose DMT research was the catalyst for the psychedelic renaissance we find ourselves in today. He also co-authored DMT: The Spirit Molecule.
Andrew Gallimore discovered that you can use an infusion pump to push DMT into your bloodstream over a certain amount of time, meaning you get to stay in the DMT space for hours.
You can even titrate to smaller doses, meaning if it’s too intense, the practitioner can decrease the flow rate of the medicine, keeping you in the hypervisual state without overactivating your nervous system.
Incredibly, even if someone needs to take a bathroom break, the infusion pump can be turned off. Within 60 seconds of turning the pump back on, the journeyer will be right back in the psychedelic space. This is great in an emergency.
DMTx isn’t a cheap endeavor, requiring 4 practitioners and medical equipment, but in the spirit of accessibility, Daniel has made it a point to offer it through his church to community members for free. Not everyone can receive this treatment for free, but there is a pathway for it.
Why is Ethical Facilitation Important?
Wrapping up our conversation, we see that Daniel McQueen and our own founder, Jimmy Nguyen, truly are birds of a feather.
They may have taken different paths (don’t we all), but the same threads permeate both of their work: ethics, care, and consent. They both believe in accessibility and transparency, careful not to fall into the trap of psychedelic cheerleaderism.
A true psychedelic professional doesn’t convince you that psychedelics are right for you; they don’t tell you their way is the right way, and they shouldn’t pressure you into an experience that you don’t resonate with.
A true psychedelic facilitator has no agenda, and only cares about your safety and helping you find the path that’s right for you, whatever that may look like.
Ultimately, leaders like McQueen and Nguyen prove that the true measure of a psychedelic professional lies not in promotion, but in a steadfast commitment to client autonomy, safety, and ethical care.
More From Our Guest:
- You can visit the Center for Medicinal Mindfulness in Boulder, Colorado
- Daniel McQueens Facilitator Training Program
- Psychedelicshine.com
- DMTx.org
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- History Repeats Itself: Learn how important it is to honor ancestral roots and bring community back into healing with Dr. Glauber Assis.
- Awaken Your Inner Child: Growing up doesn’t mean shutting down. The things we leave behind as we grow might be the key to true healing.
- Indigenous Wisdom in Clinical Psychology: More and more doctors are exploring the potential of psychedelic healing and merging it into their western practices.
- Antidepressants, SSRIs, Oh My: Like any drug or medication, learning about possible interactions is imperative to a safe healing journey, and the Spirit Pharmacist, Dr. Ben Malcolm, helps us do just that.
- Support Comes In Many Shapes & Sizes: The ins and outs of psychedelic support are dynamic and often work in tandem with the person it’s geared towards, learn what it truly means to “hold space” for someone.
- Learning More About Consumption: Take a look at a more in depth overview of popular ways to consume psilocybin-containing mushrooms.
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Frequently Asked Questions
1. Why does psychedelic cannabis emphasize using an “anxiety-inducing” sativa strain?
It sounds counterintuitive for a trauma-informed therapy, but the high-THC, intimidating sativa strain is chosen specifically to “turn up” the brain’s energy, creativity, and hyper-alertness.
To prevent a panic attack, this intense mental stimulation is intentionally paired with an older indica strain. Because the indica has aged, its THC has partially degraded into CBN (Cannabinol), which acts as a built-in sedative that neutralizes the sativa’s anxiety while leaving the mind wide awake.
2. If I just shake and tremble during a session without seeing visuals, did the psychedelic cannabis fail?
Not at all, in fact, Daniel McQueen considers a session where you “only” shake to be an incredibly successful journey. Based on Peter Levine’s Somatic Experiencing principles, shaking is the body’s natural, biological mechanism for discharging stored trauma and resetting the nervous system.
Psychedelic cannabis acts as a somatic (body-based) tool, allowing you to process and release deep-seated emotional residue physically, without forcing your mind to consciously relive the painful memories.
3. How does coming down from psychedelic cannabis differ from classic psychedelics like psilocybin?
Psychedelic cannabis offers a unique level of user agency. While it induces vivid closed-eye visuals and a dream-like state, the “psychedelic veil” is highly responsive to your physical posture. If you open your eyes and sit up, you can immediately ground yourself back into a sober, albeit heavily “stoned,” reality.
Classic psychedelics like psilocybin or ayahuasca do not have an “off switch” or a boundary that clear; once you ingest them, you are fully immersed in the experience for its duration, regardless of your posture.
4. What is the logistical difference between smoking standard DMT and undergoing a DMTx session?
A standard smoked DMT experience is like being propelled through a wormhole via rocket ship: it is incredibly shocking, comes on in 15 seconds, and evaporates in 5 to 15 minutes, often just as you are starting to orient yourself.
DMTx changes the mechanics by using an medical infusion pump to slowly push DMT into the bloodstream over several hours.
This allows practitioners to perfectly titrate (adjust) the flow rate, keeping the journeyer in a stable, prolonged hypervisual space that they can actually explore and integrate.
5. Why does McQueen recommend a “multimodal” approach instead of relying on one breakthrough medicine?
Relying entirely on a single massive psychedelic session places immense pressure on a person to “heal all their trauma at once,” which is rarely effective or sustainable. The Center for Medicinal Mindfulness uses a multimodal approach by layering lighter experiences like cannabis or ketamine before and after a larger psilocybin or DMT journey.
This multi-substance framework takes the pressure off the client, eases the nervous system into deep states of vulnerability, and provides a gentler runway for integration.
References
Kuhfuß, M., Maldei, T., Hetmanek, A., & Baumann, N. (2021). Somatic experiencing – effectiveness and key factors of a body-oriented trauma therapy: A scoping literature review. European Journal of Psychotraumatology, 12(1), 1–17. https://doi.org/10.1080/20008198.2021.1929023
Scaer, R. C. (2001). The neurophysiology of dissociation and chronic disease. Applied Psychophysiology and Biofeedback, 26(1), 73–91. https://doi.org/10.1023/a:1009571806136
Van Der Kolk, B., & Van Der Hart, O. (n.d.). Pierre Janet & the Breakdown of Adaptation in Psychological Trauma. Retrieved July 6, 2026, from https://www.besselvanderkolk.com/uploads/docs/janet_am_j_psychiat.pdf
